Lupus Nephritis is a disease caused by Systemic Lupus Erythematosus (SLE).  This occurs when lupus triggers the immune system to inflame and attack the kidneys. While many sufferers may initially pass this off as just another lupus flare-up, nearly half of those suffering from lupus will develop this secondary disorder at some point.  

Symptoms

The symptoms of Lupus Nephritis will vary depending on which of the five stages of the disease you are in. A kidney biopsy is needed to fully determine the stage of the disease. Some of the most common symptoms can include:

  • Increased Urination
  • Sudden Swelling in the Extremities
  • Foamy Urine
  • High Blood Pressure
  • Fever
  • Joint Pain and Swelling

Risk Factors

As far as we know, there are not many known risk factors for Lupus Nephritis. In fact, there are mainly two – sex and ethnicity. While women are more likely to develop lupus, men most commonly develop Lupus Nephritis. Asians, Hispanics, and Blacks face a higher risk than Whites.

Diagnosis

Lupus Nephritis is typically diagnosed after a series of blood tests, ultrasounds and biopsies of the kidneys, and urinalysis. For most patients, a rheumatologist will order a urinalysis during routine appointments. This is to monitor any changes in your kidneys. It can also check for antibodies that could indicate a higher risk for Lupus Nephritis. A biopsy is typically only ordered in serious cases when kidney damage is suspected.

Lifestyle

Because it can cause high blood pressure, a low sodium diet is typically recommended. Avoiding processed food and red meat is a good recommendation as well. Consider setting up an appointment with a nutritionist to evaluate current needs.

Treatment Optionslupus nephritis

To date, there is no cure for Lupus Nephritis. There are treatment options available to reduce symptoms, slow progression, encourage remission, and prevent the need for a kidney transplant. These treatments are primarily prescription medication and may include:

  • Steroids
  • Mycophenolate
  • Benlysta
  • Cyclosporine
  • Lupkynis
  • Tacrolimus

Keep in mind that with many of these treatments, there can be an increased risk for cancer and infections.  For those with advanced kidney failure, dialysis may be needed.

With proper medication and a healthy diet, the effects of Lupus Nephritis can be lessened. Speak with your physician to find the best treatment options for you. Contact our kidney specialists at Richmond Nephrology Associates.